Register Now for Upcoming CTSC Workshops in Grant and Proposal Writing and Biomedical Publications!

Weill Cornell Medicine Clinical and Translational Science Center

Presents

WRITE WINNING NIH GRANT PROPOSALS

May 10, 2016, RSVP here

& May 11, 2016, RSVP here

8:15AM-5:00PM

Griffis Faculty Club, 1300 York Avenue at 69th Street

This seminar comprehensively addresses both practical and conceptual aspects that are important to proposal-writing success. It is designed for faculty members and administrative staff who have had some exposure to writing grant applications. Principles and fundamentals of good proposal writing are emphasized, along with ‘how-to’ practical tips and strategies. Topics covered include idea development, maximizing programmatic relevance to the targeted agency, selecting the correct grant mechanism in which to package and present the idea, use of the review process to inform the writing of the application, and how to write for reviewers. In addition, strategies for writing each part of the application are presented, along with examples that illustrate how each section should be crafted. This seminar teaches new investigators how to write a competitive grant application; the content of the program is appropriate for senior graduate students, post-doctoral research fellows, and nontenure-track faculty members who have not written a successful grant application.

WRITING A SUCCESSFUL CAREER DEVELOPMENT AWARD PROPOSAL

May 12, 2016

12:30pm – 5:00pm
Belfer Research Building, 413 East 69th Street, Room BRB 302 B/C

RSVP

This half-day seminar is for Career Development Award (CDA) candidates and their mentors. It emphasizes the partnering between the candidate, mentor, and institution that is necessary to make these proposals successful, resulting in protected time for research. The National Institutes of Health’s mentored K Awards and Ruth L. Kirschstein F32 National Research Service Award for individual post-doctoral fellows are used as representative applications.

WRITING SUCCESSFUL BIOMEDICAL PUBLICATIONS

May 26, 2016

8:15AM-5:00PM

Griffis Faculty Club, 1300 York Avenue at 69th St.

RSVP

This comprehensive seminar includes advice on how to most efficiently produce the data needed to publish, how to compose a manuscript with maximal clarity and precision, how to avoid conflict of interest, and how to decide who should be included as co-authors and in what order. In addition, tips and strategies are provided regarding how to perform a literature search; how to choose journal; and how to understand that journal’s review process, including relating to its editors, responding to its reviewers, as well as navigating its resubmission process.

For more information, please email or call 212-746-6277

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Join Us for the Next Research in Progress Luncheon, Friday, May 13, 2016

WEILL CORNELL MEDICINE
CLINICAL & TRANSLATIONAL SCIENCE CENTER

RESEARCH IN PROGRESS LUNCH SERIES

Conducting mentored clinical and translational research from the perspective of Trainees and Scholars

Luncheon Host

Kendall Smith, MD
CTSC Associate Program Director
Rochelle Belfer Professor in Medicine
Weill Cornell Medicine

Friday, May 13, 2016
12:30-1:30pm
Weill Greenberg Building, Conference Room C
1305 York Avenue, New York, NY

Featured Presentations:

“Assessing Insulin Sensitivity and Diabetes Risk in Childhood Cancer Survivors Treated with Abdominal Irradiation”
CTSC KL2 Scholar – Danielle Novetsky Friedman, MD
Pediatrics, Memorial Sloan Kettering Cancer Center

“SEER-Medicare and Meta-Analyses of Small Renal Mass Management”
CTSC Master’s Degree Candidate – Adam Talenfeld, MD
Interventional Radiology, Weill Cornell Medicine

“Identifying Shared Mechanisms of Action between Colorectal Cancer Chemo-preventative and Chemotherapy Drugs: Thymidine Depletion by DFMO/Sulindac”
CTSC TL1 Trainee – Mavee Witherspoon, PhD
Medicine/Gastroenterology and Hepatology, Weill Cornell Medicine

Click here to RSVP

Visit the CTSC website for more information about the
CTSC Education and Training Program

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REGISTER TODAY: LGBT Communications & Health Needs Workshop on 4/7/16

Weill Cornell Medicine
Clinical and Translational Science Center (CTSC)

Presents

Cultural Competencies Training: LGBT Communications and Health Needs

All are welcome to participate in a training on Lesbian, Gay, and Transgender (LGBT) Inclusive Communications and LGBT Health Needs. Through interactive activities participants will learn how to communicate and provide care that is sensitive and inclusive for their LGBT patients and families and learn about local and national LGBT health disparities and best practices in the care of LGBT patients.

Thursday, April 7th, 2016
12:00pm-2:30pm
Weill Greenberg Building
Conference Room A/B
1305 York Avenue, New York, NY

Nelson Sanchez, MD
Chairperson of Weill Cornell Medical College’s LGBT Steering Committee

Please RSVP for the workshop (here) by April 5, 2016
**Lunch will be provided**

After the workshop, all are invited to a
Weill Cornell LGBT Mixer
Sponsored by
The Weill Cornell LGBT Steering Committee
5:30pm-7:30pm
Weill Greenberg Building
Conference Room A/B
1305 York Avenue, New York, NY
RSVP to the Mixer (here) by April 4

Questions? Please contact My Linh Novotny at ctsc-education@med.cornell.edu

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CTSC TL1 Alumna Paige Yellen Builds New Biotech Company ABC Life Sciences

Paige Yellen, headshot

Paige Yellen, PhD, is an alumna of the CTSC’s TL1 Training Program and the Founder and CEO of ABC Life Sciences

Moving from academia into industry can be a daunting challenge for an early-career scientist, but it’s one that CTSC education program alumna Paige Yellen, PhD, is tackling with enthusiasm and determination. Dr. Yellen is now Founder and CEO of the new biotech company ABC Life Sciences, which is developing a nanoparticle drug-delivery platform for the treatment of kidney diseases.

Her path to becoming a health tech entrepreneur began in her postdoctoral studies after earning her PhD from the Graduate Center of the City University of New York (CUNY). As a postdoctoral fellow in the laboratory of Neal Rosen, MD, PhD, at the Memorial Sloan Kettering Cancer Center (MSKCC), Dr. Yellen remembered affectionately the long nights and her excitement for her research into cancer biology. “I would sit down on the floor right next to the dark room to examine, pour over, my Western blots,” she laughed. “One of my colleagues joked that the lab should buy me a chair!”

Despite feeling a deep passion for the science she was doing, however, Dr. Yellen felt that her best skills were not yet being fully utilized. “In the beginning I thought I should want to be in academia. In the grad student world, that is often considered success,” she observed. “But I had to be honest with myself: I love science, but I didn’t want to be in a lab.”

MSKCC researcher Daniel A. Heller, PhD, is a colleague who has developed technologies that could potentially be brought to market, including the nanoparticle that is their current project. “He presented his lab’s research at an internal conference and I was so intrigued; I met with him and we decided to start a company,” she remembered. Taking the Weill Cornell Medicine graduate course From Bench to Bedside: Business Fundamentals for Entrepreneurial Scientists also proved inspiring. During that class, Dr. Yellen pitched ABC Life Sciences to a panel of venture capitalists against six other teams—and won. As her thoughts turned more towards becoming an entrepreneur, she found having the right mentors to be another invaluable asset. Attending biotech meetings allowed her to meet mentors who were willing to listen or to help connect her with others.

Now fully committed to making the company a success, Dr. Yellen is learning the ins-and-outs of the industry through hands-on experience, including being a current fellow of the Entrepreneurship Lab Bio and Health Tech NYC, a highly competitive initiative founded by the New York City Economic Development Corporation (NYCEDC) to educate and support early-career tech entrepreneurs. She thinks ABC Life Sciences is serving an important need right now. “I named the company ABC Life Sciences because I wanted to reflect on the ways research creates a sequence of building blocks, like letters, that then lead to translation. There really is very little in terms of finding new ways to treat kidney diseases, despite a push for more research funding,” she noted. “It’s just been accepted that these patients will eventually go on dialysis, so there’s a great opportunity to transform care.” She’s now hoping to shepherd the nanoparticle technology through important milestones of the developmental pipeline, from proof-of-concept studies through Phase II studies in humans.

As part of her training, Dr. Yellen praised the diverse offerings of the CTSC’s TL1 program. “I learned so much. The electives were so varied and the breadth of applications for clinical research was great. At the time, I thought about how I could apply what I was learning to academia as a post doc, but now I’d come at it from a different perspective as an entrepreneur. I’ve saved all the books! I loved being in the program, because I had another outlet, another perspective, outside of the tunnel vision that might come from focusing too intensely on bench work alone.”

As for the lessons she has learned as she launches this new endeavor, Dr. Yellen described the following as essential characteristics for a successful entrepreneur, in her opinion. “You have to be open and vulnerable to other people. Talk to people, but be a little selective and make sure there’s an objective. At the beginning, my attitude was, ‘just get out there,’ and now I’m more focused. One of the most essential things is being able to communicate yourself—your idea—in a very brief encounter with someone: who you are and what you’re doing. You need to be optimistic as an entrepreneur because there are often too many reasons to say ‘no.’ But you also have to be very realistic about your own product. You can’t be so attached just because it’s yours. You have to be creative: there is not just one avenue to get something; you have to think of different ways to get to a goal.”

“Paige Yellen really exemplifies everything we hope our students can become,” Julianne Imperato-McGinley, MD, program director of the CTSC, noted. “There’s an absolute commitment to scientific rigor and excellence, but also a desire to make a difference and really impact the lives of people living with disease. Starting a business is an intimidating proposition, but Paige is embracing the challenge of it.”

Acknowledging the many different types of personalities that can be successful, Dr. Yellen observed, “I’m more of a risk taker. I want to be successful. I want to be happy. I’m willing to take a risk to achieve those things.”

And if an idea doesn’t become reality? “I have lots of ideas; I’ll move to the next thing and move forward,” she said, with a smile.

For more information about educational opportunities at the CTSC, visit here.

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Register NOW for CTSC Drug and Device Development and FDA Regulations Workshop

LEARN ABOUT THE DRUG AND DEVICE DEVELOPMENT PROCESS

FREE SKILLS ACQUISITION WORKSHOPS

Sponsored by the Clinical and Translational Science Center (CTSC)

Register now:

weill.cornell.edu/ctsc/news/resources/2016_Registration_SpringSeminars.doc

• Drug Development and FDA Regulations

This course provides an overview of the drug development process, including GLP, GCP, and GMP processes. It is intended for early stage investigators from various disciplines with a need to develop and understanding of the drug development process.

Monday, April 18, 2016, 8:15am – 5:00pm
Weill Greenberg Center, 2nd floor

• Medical Device GCP Overview

This course provides information across the full range of medical device clinical trial activities as an ideal source of information for those new to clinical research and those requiring information specifically relating to regulatory and practical aspects of medical device clinical research.

Friday, April 22, 2016, 8:15am – 5:00pm
Belfer Research Building, 413 East 69th Street, room BRB 302 A/B

Seats are assigned on a first-come, first-served basis.
Breakfast and lunch will be provided.

For more information please email: sec3001@med.cornell.edu

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CTSC Offers Optimizing the Practice of Mentoring Workshop. RSVP by March 25!

Weill Cornell Medicine 

Clinical & Translational Science Center 

 

Optimizing the Practice of Mentoring:

How to be an Effective Research Mentor

 

The objective of this workshop series is to prepare junior and senior faculty to be effective research mentors through presentations by experts in the field of faculty mentoring. 

The 2-day format of morning lectures and afternoon small-group facilitated discussions will engage learners through presentations and interactive activities. Mentors and mentees at all different professional levels are welcome to attend the morning sessions on both days. The afternoon small group sessions are for designed for mentors only and require a 2-day commitment.

The presenters will also introduce attendees to a free online curriculum for mentor training that is designed to improve users’ mentoring knowledge and skills, while encouraging reflection about one’s mentoring behaviors and providing tools to support the mentoring process.

March 29th and 30th, 2016
1300 York Avenue, New York, NY

The Griffis Faculty Club

Anne Marie Weber-Main, PhD 
Associate Professor of Medicine, Director of Faculty Mentoring,
Medical School, University of Minnesota

Esam El-Fakahany, PhD
Professor of Experimental & Clinical Pharmacology
Associate Dean for Research & Graduate Studies
College of Pharmacy, University of Minnesota

Please RSVP (here) by March 25, 2016

http://weill.cornell.edu/ctsc/training_and_education/flyer_optimizing_practice_mentoring_be_effective_mentor.html

Workshop Schedule

Tuesday, March 29

8:30am: Registration and Breakfast

9:00am – 12:00pm: Introduction to Mentoring Best Practices

12:00 – 1:00pm: Lunch

The small group sessions are designed for mentors only and require a 2-day commitment, advanced sign-up is requested

1:00 – 4:00pm: Competency-Based Mentor Training (small group sessions)

Competencies covered may include:

  • Aligning Expectations
  • Effective Communication
  • Addressing Equity and Inclusion

Wednesday, March 30

8:30am: Registration and Breakfast

9:00am – 11:00am: Mentoring Maladies: Recognizing and Overcoming Challenges in Your Mentoring Relationships

11:00am – 12:00pm: Lunch

The small group sessions are designed for mentors only and require a 2-day commitment, advanced sign-up is requested

12:00 – 2:30pm: Continuation of Competency-Based Mentor Training (small group sessions)

Competencies covered may include:

  • Fostering Independence
  • Promoting Professional Development
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Weill Cornell Graduate Student Fon Powell And CTSC Partner On NYC Health Tech Award for Novel Salt-Monitoring Technology

Fon_Headshot

Fon Powell, a graduate student in computational neuroscience at Weill Cornell Medicine, won a 2016 grant from the Pilot Health Tech NYC program to develop S.A.L.T., a novel device for self-measuring salt intake.

On Wednesday, February 17, 2016, the New York City Economic Development Corporation (NYCEDC), in partnership with Health 2.0 and Blueprint Health, announced the winners of the latest round of pilot funding from Digital Health Marketplace (formerly Pilot Health Tech NYC),  a groundbreaking competition to support healthcare technology entrepreneurship in NYC by matching start-up companies who have an innovative technology with an institutional host who will help support it. This year, one of the winning teams is Weill Cornell graduate student Fon Powell and the Weill Cornell Clinical and Translational Science Center (CTSC). As the innovator, Ms. Powell and her company Sodium Analyte Level Test LLC (S.A.L.T.) have developed a portable, smart phone-based home urinary analysis test that will allow users to conveniently self-monitor sodium intake, while providing physicians and researchers a mechanism to gather data on salt levels. As her host, the CTSC will support Ms. Powell in gathering pilot and proof-of-concept data in human participants that will help her expand the business and meet regulatory requirements.

For Ms. Powell, a PhD student in computational neuroscience, the idea for the company came in 2014 when she was introduced to the technology during the course Bench to Bedside: Business Fundamentals for Entrepreneurial Scientists at Weill Cornell. Although her academic interests were in an unrelated discipline, the potential of this technology to help those living with hypertension, which disproportionately impacts African American communities and has affected members of Ms. Powell’s own family, spoke to her. Ms. Powell expressed her gratitude to Weill Cornell Medicine physician Samuel J. Mann, MD, and biostatistician Linda Gerber, PhD, MA, who developed the algorithm used by the technology.

Since then, the journey to becoming an entrepreneur with a young company has been helped by several supportive organizations along the way. “The NYCEDC has been really great in supporting early start ups,” she noted, acknowledging not only the Digital Health Marketplace program, but also the Entrepreneurship Lab Bio and Health Tech NYC, which she described as a “six-month mini-MBA” that helped her develop a business plan and provided networking and training to tackle the various challenges of launching new health technology. She also credited the support of the Stonybrook Center for Biotechnology, which created additional opportunities for her to pitch the project and helped her access patent information that would have been prohibitively expensive for a young company to otherwise obtain. In 2015, Ms. Powell took first place in the Women’s Business Enterprise National Council Student Entrepreneur Program, which has also helped her further her company. “People want to help young entrepreneurs,” she observed of her experience. “You have to learn how to ask for the help.”

Ms. Powell and the CTSC will collaborate in a number of ways. “As a grad student, I knew of the CTSC because of its educational activities,” she said, having successfully completed  the CTSC’s Introduction to 3D Printing workshop, which offered a three-session overview of 3D Printing, including using medical imaging data for 3D printing and 3D scanning in medicine and biomedical research. “But when James Holahan (Associate Director of Center Operations of the CTSC) told me, ‘I think we can help you with your work,’ I said, ‘Tell me more.’” While working on her Digital Health Marketplace project, Ms. Powell will have access to a variety of CTSC services, including the 3D Printing Core to rapidly design and manufacture the devices, the Translational Research Support Team to recruit patients and facilitate research visits, the Outpatient Clinic to perform clinical measures, the Core Laboratory to analyze samples, and Biomedical Informatics to aid with data management.

“We are thrilled to support Fon in the development of S.A.L.T.,” said Julianne Imperato-McGinley, MD, program director of the CTSC. “This novel approach to self-monitoring salt levels will help physicians and researchers gain a greater understanding of this important public health issue, while empowering individuals to take control of their personal health.”

For more information about Digital Health Marketplace, visit here.

For more information about S.A.L.T., visit here.

For more information about CTSC research support services, visit here.

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Interested in becoming a Certified Clinical Research Professional? SoCRA Certification Q&A – February 16th

SoCRA CCRP Certification – Q&A Session

Sponsored by the Clinical and Translational Science Center (CTSC) and Hospital for Special Surgery

Tuesday, February 16, 2016

10:30AM-11:30AM

Belfer Research Building (413 East 69th St), Rooms BB 302 B/C

 

Are you interested in becoming certified by SoCRA as a Certified Clinical Research Professional (CCRP)?

Do you have questions about eligibility and benefits of certification?

Join us to speak directly with SoCRA representatives, ask questions and learn if CCRP certification is right for you. Attendees will be the first to receive instructions to register for the exam on April 25, 2016.

Society of Clinical Research Associates (SoCRA) established the Certification Program for Clinical Research Professionals in order to create an internationally accepted standard of knowledge, education, and experience by which clinical research professionals will be recognized by the medical research community.

Clinical Research Professionals (CRPs) may function as a clinical investigator, research nurse, pharmacist, administrator, coordinator, data manager, quality assurance manager, regulatory affairs manager or educator in clinical trial management. Those individuals so approved may use the title “Certified Clinical Research Professional” or “CCRP.”

Questions? Please contact James P. Holahan, CCRP at jph2003@med.cornell.edu

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Recruiting for CTSC Summer Medical Student Fellows 2016 – Applications Due 2/29/2016

Weill Cornell Clinical & Translational Science Center

SUMMER INTENSIVE FELLOWSHIPS IN CLINICAL & TRANSLATIONAL RESEARCH FOR MEDICAL STUDENTS

APPLICATIONS DUE BY 5PM ON MONDAY, FEBRUARY 29, 2016

Individuals from underrepresented groups, disadvantaged backgrounds, and with disabilities are strongly encouraged to apply

The CTSC Summer Intensive in Clinical/Translational Research Fellowship for Medical Students is an 8-week continuous, full-time program that provides medical students who are between the first and second year of medical school with an introduction to basic, translational, or clinical research.  The program includes a summer research project conducted within the June to August timeframe, under the mentorship of a CTSC faculty member, attendance at weekly research seminars in the department that the student is conducting research, completion of a 2-day CTSC research grant writing workshop, a poster or oral presentation of the student’s project at the following year’s WCMC Medical Student Research Day, and a written work product.  The student’s participation in this program may qualify for WCMC 4 weeks elective credit.

The fellowship includes a stipend in the amount of $1500 and may be combined with Federal Work Study funds for a total combined funding of $3,000.

To apply, please visit the RFA link:
http://weill.cornell.edu/ctsc/training_and_education/summer_fellowships_medical_student.html

Contact My Linh Novotny at ctsc-education@med.cornell.edu if you have questions.

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CTSC Bioinformatics Core offers NextflowWorkbench training

The biomedical informatics core of the CTSC is offering the NextflowWorkbench language to help write data analysis pipelines/workflows. NextflowWorkbench takes advantage of the Nextflow middleware and makes it possible for beginners in bioinformatics to quickly assemble efficient, parallel, portable, and reproducible workflows.

Developed workflows are portable. They can run either on personal computers  as well as on compute clusters or commercial clouds.

The training session (1.5hr) will provide an introduction to the development of workflows with NextflowWorkbench. In this session, trainees will create a workflow useful to analyze RNA-Seq data, including:

  1. Download read files from the Short Read Archive (SRA)
  2. Estimate quality control measurements (with FastQC)
  3. Estimate counts against the human transcriptome (with Kallisto and an Ensembl Transcript sequence database)
  4. Combine these counts into one matrix, a pre-requisite to using these counts for differential expression (e.g., with the MetaR Limma Voom analysis protocol)

Here is a diagram of the pipeline that we will develop during the training:

Training-Workflow-overview

NextflowWorkbench is part of the Data Analysis Workbench and is being developed to facilitate data analysis for biomedical scientists with minimal computational skills. The software is fully functional, open-source and provided free of charge.

The software runs as a desktop application with an interactive user interface, on MacOS X (10.8.3+) and Linux (with support for docker).

Training and assistance in the use of the software is offered to investigators who hold an appointment in one of our CTSC institutions (i.e., Weill Cornell, MSKCC, HSS, and Hunter College).

See http://workflow.campagnelab.org for software and video tutorials.

Training Sessions:

Users interested in learning how to use the software are encouraged to attend one of the monthly training sessions. Training sessions are held on select Tuesdays at 10:30 AM.

The sessions are limited to a small number of participants and pre-registration is required. Please use the registration form (http://goo.gl/forms/tW13LBjjkr) to reserve a seat. The first training session will be held Feb 2nd 2016.

Pre-requisites:

Some knowledge of the Linux/UNIX command line is needed to develop new Workflows, but the training does not require strong proficiency. Some elements of programming may also be beneficial. Trainees will be requested to precisely follow the installation instructions to download and install the software on their laptop before attending the training session.

This software is provided by the Biomedical Informatics Core of the Clinical and Translational Science Center and by the Campagne laboratory. Please contact Dr. Fabien Campagne if you have any questions or comments at 646-962-5613.

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